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Glosar

Termeni din cercetarea peptidelor

Amino acid
The building block of peptides and proteins. There are 20 standard proteinogenic amino acids in human biology.
Agonist
A molecule that binds a receptor and activates it, producing a downstream biological response.
Bioavailability
The fraction of an administered dose that reaches systemic circulation in active form.
Cleavage
The enzymatic or chemical breaking of a peptide bond, releasing a fragment or active sequence.
Half-life
The time required for the concentration of a molecule in the body to reduce by half.
Incretin
A class of metabolic hormones (e.g. GLP-1, GIP) that stimulate insulin secretion in response to food.
Ligand
Any molecule — including a peptide — that binds to a receptor to elicit a biological effect.
Neuropeptide
A peptide that acts as a signalling molecule in the nervous system, often modulating neurotransmission.
Pharmacodynamics
The study of what a drug does to the body — its biochemical and physiological effects.
Pharmacokinetics
The study of what the body does to a drug — its absorption, distribution, metabolism and excretion.
Receptor
A protein on or inside a cell that recognises and binds a ligand to trigger a cellular response.
Recombinant
Produced by inserting a gene encoding the peptide into a host cell that synthesises it.
Secretagogue
A substance that promotes the secretion of another, such as a growth-hormone-releasing peptide.
Subcutaneous
Administered into the tissue layer just under the skin — a common route for peptide research compounds.
Synthesis
The chemical or biological assembly of amino acids into a peptide chain.